PCOS, the usefulness of practising physical activities Have you just been diagnosed with Polycystic Ovary Syndrome (PCOS) and your doctor has advised you...
SPIOMET4HEALTH’s virtual kick off meeting The SPIOMET4HEALTH project kicked off by a virtual Consortium meeting on 8-9 April 2021, which brought...


SPIOMET4HEALTH is a project that aims to provide a novel treatment for adolescent girls and young adult women with Polycystic Ovary Syndrome (PCOS). PCOS negatively affects the health and quality of life of approximately 110 million women who suffer from this syndrome, as well as their offspring. PCOS has an impact on the emotional, physical, social functioning and behaviour, and family-related activities.

Women with PCOS may have infrequent or prolonged menstrual periods or excessive levels of male hormones (androgens), which are usually present in women in small amounts. Those affected by the syndrome can also suffer from hirsutism, acne and abnormal body fat distribution, which in turn, tends to decrease self-confidence and self-esteem. Consequently, approximately 40% of women with PCOS are known to experience depression or anxiety.


The SPIOMET4HEALTH project represents a potential treatment for PCOS that focuses on tackling the syndrome at its root, rather than merely relieving its symptoms.

This treatment combines three medications that have already proven to be effective in the past, in a single tablet. Combining SPI (spironolactone)-PIO (pioglitazone)-MET (metformin), SPIOMET, administered daily, together with lifestyle measures, could normalise ovulation and hormones, and thus revert the alterations associated to PCOS.

Work Packages FAQs about SPIOMET4HEALTH


My name is Emelyne, I am French and I am 33 years old.
My story with PCOS started early, as I was lucky enough to be diagnosed when I was 17 years old.

Besides not having my period, I had a myriad of symptoms such as weight gain, hair loss, and hirsutism (which was the start of a long battle). At first, I was blamed like many patients to secretly snack, and told that it was nothing and I just had to take the pill to regulate my symptoms.

PCOS had an effect on my life at an early age: unable to cope with all these symptoms, I stopped dancing and competing in gymnastics, which I loved very much. The thing is, back in 2005 there were not much resources and young patients like me were lost with the whole diagnosis.


33 years old. France.

I’m Alexandra, I’m 20 years old and I was diagnosed with PCOS at 14/15 years old.
It all started because I had very irregular menstruations and, whenever I had them, on the first day my ovaries would hurt a lot and my abdomen would swell. After some tests and analysis I was diagnosed with PCOS.

The most shocking thing for me was when the doctor told me that I might had trouble getting pregnant in the future. Throughout the visit I thought I was getting along…But when I got out of the car and arrived home I immediately started crying. It wasn’t only the problem of infertility, but also everything that living with this syndrome entailed: controlling weight, hair growth, my mood, etc.


20 years old. Spain.

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