September is PCOS Awareness Month, and at SPIOMET4HEALTH we join this global movement to raise awareness of a condition that affects 1 in 10 women of reproductive age. Despite its prevalence, Polycystic Ovary Syndrome (PCOS) remains underdiagnosed, misunderstood, and without a specific approved treatment.
Since April 2021, our project has been working to change this. Through a multi-country clinical trial, we are testing a new approach that combines spironolactone, pioglitazone, and metformin (SPIOMET) in a single daily tablet, complemented by lifestyle interventions. Unlike conventional treatments that mainly mask symptoms, SPIOMET aims to address the underlying mechanisms of PCOS with the goal of achieving long-term improvements in both physical and emotional health.
Where do we stand now? Recruitment is complete and the research team is analysing the obtained clinical data. Step by step, we are building the evidence needed for what could become the first treatment specifically approved for adolescent girls with PCOS. A milestone that could impact millions worldwide.
This September is therefore a special moment for our project. Not only do we stand together with the global community for PCOS Awareness Month, but we will also gather all our partners in Barcelona for the fourth General Assembly Meeting of SPIOMET4HEALTH. A chance to reflect on progress and look ahead to the important next stages of our journey.
Exciting times, right?
Why does PCOS research matter more than ever?
Because the impact goes far beyond fertility.
PCOS affects metabolic health and increases the risk of long-term conditions such as diabetes and cardiovascular disease. Research is needed to understand the full spectrum of health implications and to offer effective, science-based treatments.
Because PCOS also takes a toll on mental health.
Anxiety, depression, and low self-esteem are common among women with PCOS, yet often overlooked. Research must shed light on these dimensions too, to ensure care addresses both physical and emotional wellbeing.
Because current treatments are not specific to PCOS.
Most options today are adapted from other uses and mainly relieve symptoms, but they don’t target the root causes. This leaves many patients with persistent health issues and long-term risks that remain insufficiently managed.
Because there is still a critical evidence gap.
Despite its prevalence, PCOS remains under-researched. Many questions about its causes, progression, and effective treatment remain unanswered. Research is essential to close this gap and deliver solutions that truly meet patients’ needs.
Because misinformation is everywhere.
PCOS patients often face a flood of contradictory advice online, from miracle diets to quick fixes without scientific basis. Research provides clarity and trustworthy solutions. Projects like SPIOMET4HEALTH are helping to fill this knowledge gap by generating evidence and supporting patients.
PCOS Awareness Month: your voice matters too
SPIOMET4HEALTH is more than a research project. It is a community working for a future where women with PCOS receive the attention and support they deserve.
This September, we invite everyone — patients, researchers, healthcare professionals, and allies — to share their views on why does PCOS research matter now more than ever. We encourage you to be part of the conversation by adding your voice. Together, we can replace myths with evidence, and isolation with support.
Click here and join us in amplifying the importance of PCOS research!
Our partner’s voices: